Sentence examples for substantiate increased from inspiring English sources

Epidemiological evidence to substantiate increased radiosensitivity among carriers is, however, sparse (Bernstein et al, 2006; Broeks et al, 2007).

Whether meta-analysis of data with incomplete historical data on risk factors such as psychiatric history is adequate to substantiate increased psychiatric symptoms in major anticonvulsants for seizure disorder deserves further assessment [ 45].

In summary (Table 1), these results show several facets of UPR activation and, therefore, substantiate increased ER-stress in the tetraspanin-transfected MM cell lines.

Additionally, we were able to substantiate increasing PSMA expression by increasing androgen deprivation on the protein level.

In vivo plasma lipoperoxidation was greater in cows fed fish oil versus soybean oil, which substantiated increased susceptibility of plasma lipoperoxidation when cows were fed fish oil.

Tunel staining substantiated increased apoptotic activity as it revealed a significantly (*** P<0.0001) higher number of tunel-positive nuclei in M. gast.

Quantitative data generated from RT-PCR further substantiated increased expression of Insulin gene among Mutants, being more pronounced at 6 12 months of age compared with their Lean littermates (values have been normalized against their Controls)).

These data are consistent with our inability to substantiate increases in trisomy 21 in cells of the sporadic AD brain.

Ultimately, more trial data may be necessary to substantiate the increased use of distal protection devices in infrainguinal interventions to justify the increase in cost, complexity, and potential risks associated with the use of this technology.

To substantiate if increased cAMP signalling facilitates a growth advantage in the AI phenotype, we then stimulated PC3 cells with the adenylyl cyclase activator, forskolin (10  μ M) and observed a marked increase in proliferation rate, which was insensitive to treatment with the PDE4 inhibitor rolipram (10  μ M; Supplementary Figure 3).

The relatively young age of onset in this population could be explained by the interplay between common genetic susceptibility background substantiated by increased consanguinity and epigenetic aberrations.