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Although the ΔF508 mutation virtually eliminates all functional CFTR protein from human airway epithelial cells, it has a substantially weaker effect on CFTR in other tissues and organisms (Ostedgaard et al., 2007; Luo et al., 2009; van Barneveld et al., 2010).
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While the VCA region is critical for yeast Las17 NPF effects, even dimerized it has substantially weaker NPF effects compared to full-length Las17 (Rodal et al. 2003).
These results suggest that among common variants captured on our genotyping platform, AS3MT SNPs are the major genetic determinants of arsenic methylation capacity in this population and that contributions of other common variants to methylation capacity are substantially weaker than the effects of AS3MT variants.
We found that the apparent effect of cholecystectomy was the strongest when it occurred 2 years or less before the cancer diagnosis, became substantially weaker when that interval was longer than 2 years, but was still statistically significant even when that interval was 20 years or more.
Only about 8percentt reported "substantially weaker demand" for such projects, the survey said.
The aliphatic amines are stronger bases than ammonia, and the aromatic ones are substantially weaker.
The material, reinforced carbon-carbon taken from the shuttle Discovery, is substantially weaker and less flexible than fiberglass.
Revenue from its wireless chip unit fell 8 percent, to $658 million, partly because of "substantially weaker demand" for wireless baseband chips.
Although some of the counterfeit parts were already in use when the fraud was discovered, metallurgical testing revealed that they were not substantially weaker than the proper bearings.
Many had expected the panel, known by its acronym, Unmovic, to be substantially weaker than its predecessor, the United Nations Special Commission, known as Unscom.
"The claims data was substantially weaker than expected.
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