Furthermore, a number of well-developed disease specific and generic measures using the same question format have been substantially validated, and therefore provide some evidence of construct validity.
Mr. Perciasepe said, "I believe the study substantially validates some of the basic science behind the regulations, with real-world data".
Next, we performed the MTT assay in the other cancer cell lines that we had found to overexpress CSB MGH, USBB, PC3, MCF7 and T47D), substantially validating our findings that CSB suppression dramatically reduced the viability of cancer cell lines characterized by its overexpression.
What will validation validate?
Use of the U.S. EPA-prescribed parameters yields predicted PbB levels that substantially exceed the validated O'Flaherty model predictions.
Also, the challenge posed by the recently duplicated genome of polyploidy salmonids remains the same, although the number of markers from which high-quality ones can be validated is substantially increased.
The burden of major infectious diseases that disproportionately affect the health of women and children in low- and middle-income countries can, in some circumstances, be reduced substantially by implementing scientifically validated and evidence-based public health interventions, e.g., vaccination for diarrheal disease caused by rotavirus infection, insecticide-treated bed nets for malaria.
Internal validation overestimated the performance of the models, and each has substantially worse performance when externally validated.
Similar to drm mutants, no effect on methylation was recently reported for P. patens rdr2 mutant35, which we validated here while substantially expanding our analysis to a larger genomic portion (80 vs. 20%; Supplementary Fig. 8a and Supplementary Table 2).
