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This and perhaps other multi-gene assays can help define a group of patients for whom chemotherapy is futile because the biological nature of the tumour is such that it is substantially unresponsive to such agents.
Similar(59)
After analyzing the data more carefully it became apparent that the fraction of unresponsive cells across the time-course of tamoxifen administration did not substantially change and stayed in the 31% to 46% range.
All three mutants were responsive to SAG, showing that they were not disabled, but demonstrated substantially reduced 20(S -OHC binding and reS -OHCveness, with the mSmo Y134F bindingompletely unresponsive.
We have shown that growth of cancer cells unresponsive to an allosteric mTOR inhibitor can still be sensitive to mTOR kinase blockade, with AZD8055 substantially inhibiting growth in TamR and MCF7-X cells (IC50 18 and 24 nM, respectively).
While her results are consistent with our finding that local Māori are almost entirely unresponsive to changes in economic opportunities, our results suggest that mobility in response to economic opportunities has increased substantially for non-local Māori since the reform period.
"He was quite unresponsive.
She was simply unresponsive.
He was completely unresponsive.
She is extremely unresponsive.
He's unresponsive".
She wasn't unresponsive".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com