Because of a reduced number of tools for the examination of OGlcNAcylation compared to the number for phosphorylation, including in particular a limited repertoire of antibodies, the absence of convenient radiolabeling methods, and more challenging synthetic methods, the effects of OGlcNAcylation on protein structure and function are substantially less well understood.
The molecular mechanisms of variations in individual longevity are not well understood, even though longevity can be increased substantially by means of diverse experimental manipulations.
Moreover, the outcomes of patients with the same stages following surgery are substantially different, and such large discrepancies have not been well understood [ 31, 32].
Background:Ovarian cancer incidence differs substantially by race/ethnicity, but the reasons for this are not well understood.
Currently, it is well understood that capping molecules (ligands), which are intentionally formed on surface of NPs during their synthesis, change substantially surface properties of NPs.
Mankind has benefited substantially from these products, but the health implications of long-term exposure to low levels of these compounds are not well understood.
Additionally, the B7.5 network of Ciona is not substantially better understood.
In recent years interest increased substantially to understand the Musa genome.
However, the mechanism by which their metabolic rates vary so substantially remains poorly understood at both the physiological and the mitochondrial (mt) levels (Lane 2006; Pontzera et al. 2010).
Basically, I asserted that Allais' effect was more important than his paradox, despite the fact that it was substantially less well documented and understood.
Specialization of Ur. sapphirina on annelid hosts demonstrates that the host breadth of mosquitoes is substantially broader than previously understood.
