Sentence examples for substantially stabilized from inspiring English sources

Our results, however, indicate that the mechanistic shift does not directly lead to enhancement of ORR activity once water molecules solvate the N-Gr/Cu(111) surface via substantially stabilized intermediates such as O, OH, and OOH.

In the presence of the proteasome inhibitor MG132, however, PTENK62R was substantially stabilized (Fig.  5D, lane 3).

The presence of a single disulfide at either position 54 or 107 substantially stabilized the proteins, resulting in Tm values of 33 and 45 °C, respectively.

Interestingly, these mutations did not abolish conformational change, although the native state of tengpinΔ51L159QI162QI170Q was substantially stabilized (t1/2=60 h) in comparison with tengpinΔ51 (t1/2=5 h) (Table 2).

NEMO1 120 des3C/C54) and NEMO1 120 des4C/L107C) showed [urea]50 values of 1.5 2.0 M, indicating that the presence of a single interchain disulfide bond at position 54 substantially stabilized the protein.

This mutational pair recreate a kissing loop interaction that is substantially stabilized by additional hydrogen bonds and potentially increased stacking energies, suggesting that slightly altered stability of the structure alters both absolute editing level as well as thermo-sensitivity of the whole multi-duplex structural complex encompassing the three paralytic sites.

Considering that the capping and close-to-capping units tend to have more sequence diversity and more conformational variation, it could be also generally true that a T/SxxH motif close to the terminal repeats contributes little or even negatively to stability with respect to Ala substitution, but substantially stabilizes the global conformation when located in the middle of a long stretch of ARs.

In these cases, carbon coating in a vacuum evaporator can substantially stabilize the sections and make them resistent to the electron beam.

It was shown that a covalent binding of the biliverdin chromophore to a Cys residue via thioether group substantially stabilizes the spatial structure of NIR FPs.

Simultaneous deletions of residues 1 10 and 211 229 substantially stabilize Rpn4, and yet, do not impair its transcriptional activity [28], [29].

In the present study we have shown that locally adapted alleles substantially stabilize postzygotic isolation (fig. 2).