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We also note that in substantially smaller genomes, the apparent library complexity is expected to be lower because the number of positions from which sequencing library fragments can originate is smaller.
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Arabidopsis, which has undergone genome duplication as well, has a substantially smaller genome (~120 Mb) and gene complement compared to rice.
This yield suggests that directed MLPA, expanded to include additional ASD loci, would represent one option for clinical testing as the cost is substantially smaller than genome-wide arrays.
This appears to be substantially smaller than the genome size of the congeneric red imported fire ant, S. invicta, estimated at 753.3 Mb using flow cytometry [ 8].
Meanwhile, their absence in A. spinosum might explain the substantially smaller and less complex genome of this species [ 32].
The total content of methylated cytosines in Drosophila is thus comparable to those in the E. coli genome, albeit the latter genome is substantially smaller (Table 1).
This suggests that these regions are incompletely assembled prophages, and that the true number of prophage copies in the genome is substantially smaller.
Because of this data-generation bias, the amount of sequence data available for non-coding regions of the human genome is substantially smaller than for coding regions, but the extensive evidence from SNP data presented above implies that it is likely that some cancers may at least be partially driven by regulatory, splicing, or miRNA mutations.
In contrast, ET3-1 conoains no plasmids and the acquisition of MGEs has not yet led to substantial genome expansion on the scale of that observed among Yersinia; in comparison with other sequenced SA genomes, ET3-1 isubstantiallyly smaller (Table 1).
It is interesting to note that the largest P. pacificus microsatellites detected in the genomes assembly are substantially smaller than the largest C. elegans microsatellites, which have repeat units greater than 68 (Seyfert et al. 2008).
Because the LTR elements employed in this study were limited to those having both LTRs and at least remnants of protein domains, the total counts are substantially smaller than those within the various genome project papers, which include solo LTRs, fragments, and nonautonomous elements.
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