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Ice would still be expanding but at a substantially slower rate than recent estimates.
The nanomechanical data, Raman spectroscopy and SAXS support the hypothesis that intrafibrillar mineral etches at a substantially slower rate than the extrafibrillar mineral.
Ad tech companies that show sales costs growing at a substantially slower rate than gross margin growth are good bets.
Overall these GSK compounds were equally effective at blocking Orai1 and Orai3, and inhibition occurred at a substantially slower rate than La3+.
Application of the two novel compounds GSK-7975A GSK-5503A503A at 10 μM concentrations also resulted in complete Orai1 current inhibition, but at a substantially slower rate with a t1/2 in the range 75 100 s (Fig. 2A and E).
The GSK blockers inhibited Orai1 and Orai3 currents with an IC50 of approximately 4 μM and exhibited a substantially slower rate of onset than the typical pore blocker La3+, together with almost no current recovery upon wash-out over 4 min.
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A. bottimeri failed to establish, and the other two have not substantially slowed rates of mesquite spread (Zachariades et al. 2011).
The results presented in Fig. 2 indicate that a mutation in arcA results in a substantially slower growth rate of cells under aerobic conditions while the growth rate of strains carrying mutation in either crp or etrA was identical to that of wild type MR-1, consistent with previous reports [1], [11], [13] [14].
Knocking down of MYC using shMYC in TC71 and MHH-ES Ewing sarcoma cell lines resulted in a substantially slower proliferation rate and tumorigenicity when compared with control cells (Fig. 4B and C and Supplementary Figs S7 and S8).
We find that the hyperarid core of the Central Atacama has substantially slower erosion rates than its eastern and western margins; however, even the driest part of this transect has erosion rates comparable to those of other deserts, ranging from 0.2 0.4 m/Ma.
Detterbeck and Gibson's review of the natural history of lung cancer reports that conventionally detected NSCLCs have rapid doubling times averaging 135 days, while those detected in CT screening programs have substantially slower growth rates of 480 days [ 15].
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