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Reconstitution of the CD4 cell pool exhibits a biphasic pattern, with a rapid increase during the first 3 months, due to redistribution of memory cells from lymphoid tissue, followed by a substantially slower increase [ 22, 28].
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"A reversal of these increases all point to substantially slower growth in the first quarter," said David Resler, chief economist at Nomura Securities International.
However, if dominant fitness costs are associated with the dominant resistance alleles found here, such costs could substantially slow the increase in these dominant alleles (Carrière and Tabashnik 2001).
An important observation is that the forward rate of conformational closing (k2, Scheme 1) for mismatched dNTP incorporation is comparable with that for correct dNTP incorporation (though with significant increase in Kd), while the maximum rate of nucleotide incorporation (kpol) is substantially slower (also with significant increase in Kd,app) (Table 2).
It was found that the ester bond hydrolysis rate was substantially slower for PLGA-capped particles and that the rate increased with particle size.
(1) The base case, which approximates a forest-grown tree, shows that the requirement that basal trunk diameter Db ∝ H1.5 (where H is total tree height), to prevent buckling, substantially slows the height growth rate with increasing tree size, as is observed in real trees.
He finished in 62 35, substantially slower than Salazar's estimate.
"I was substantially slower and my reaction to the ball was slower".
Ice would still be expanding but at a substantially slower rate than recent estimates.
The cervix dilated substantially slower in the active phase.
In contrast, mTORC1 substrates were phosphorylated substantially slower.
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CEO of Professional Science Editing for Scientists @ prosciediting.com