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The introduction of the seven-valent pneumococcal conjugate vaccine (PCV7) has substantially prevented the incidence of pneumococcal invasive diseases caused by vaccine serotypes in developed countries such as the United States, France and Canada [3], [4] with extended benefits to non-immunized individuals by the herd-immunity.
Thus necrosis resulting from energy failure alone was substantially prevented by mtCsA.
All these effects were substantially prevented by glutathione, which effectively removes reactive oxygen species including peroxynitrite (5).
Indeed, the addition of DES substantially prevented damage nearly as efficiently as GSH, although only at 90 min.
Evidence from developed countries shows that mortality from these can be substantially prevented using population-wide and individual-based strategies.
When Fra-1-siRNA was transfered into HT-29 cells, the mesenchymal-like morphological conversion stimulated by IL-6 was substantially prevented.
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does not substantially prevent implementation of the requirements of this section and the purposes of this part.
However, existing barriers especially the investment barriers substantially prevent the low carbon technologies and service from being employed effectively.
Nilotinib pre- and post-treatment substantially prevents the MPTP-induced increase in c-Abl activity compared to MPTP treated mice and there is no effect on c-Abl activity in the mice with nilotinib only (Fig. 2e and f).
He said: "For the cost of providing a dual carriageway on a few hundred metres of the A9, we could substantially prevent these deaths amongst some of the most vulnerable people in Scotland and prevent families and communities suffering this loss.
Most importantly, blockage of lipid raft organization via the depletion of cholesterol by MCD substantially prevents avicin D-mediated Fas activation and cell apoptosis (Figure 4).
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