Cytotoxic activity of splenic mononuclear cells towards autologic tumor cells is substantially mediated by splenic NK cells [31].
There was little evidence that obesity, unhealthy behaviors, or use of antidepressants substantially mediated this association.
Results also indicated that sedentary behavior, but not smoking status or depressive symptoms, may substantially mediate the relationship between support and mortality.
Health insurance substantially mediates the quality of colon cancer care in the United States.
The two type II complexes utilize an unusual top-mounted Ig-like domain on IL-13R alpha1 for a novel mode of cytokine engagement that contributes to a reversal in the IL-4 versus IL-13 ternary complex assembly sequences, which are mediated through substantially different recognition chemistries.
We found that the prostanoid provokes substantially greater cytokine synthesis in orbital fibroblasts, effects that are mediated through cell-surface EP2 receptors and increased steady-state IL-6 mRNA levels.
Wang et al. stated that GRO β signaling was mediated through ERK1/2 and that blocking GRO β substantially inhibited signaling through ERK1/2.
Because we observed that the two anti-platelet drugs differed substantially in their ability to regulate systemic and vascular endothelial expression of netrin-1, we postulated that aspirin-mediated suppression of monocyte arterial accumulation could be mediated through its effects on netrin-1.
In addition, expression of the truncated etr1 1-349) fragment substantially reverses the etr1-7 ers1-2 mutant phenotype, suggesting that wild-type ETR1 receptor signaling can be mediated through the N terminus, possibly via the GAF domain [ 11].
