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With the latest decision it has quantified what "substantially" means.
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When matching voxel variance, SUVmax increased substantially (mean increase +32%and+49%9% for HD and UHD, respectively), potentially impacting outcome in the majority of patients.
Sequence coverage impacted our de novo transposable element identification rate and therefore the number of private TEs detected in each line varied substantially (mean 118.3, standard deviation 95.3).
But in 1979-96, Britain's GDP rose substantially, which means that the poor are getting a smaller slice of a much bigger cake.
They fear that once the legislation emerges in its final form, it will not clearly define what "substantially similar" means in its discussion of how state disclosure rules must approach the requirements of federal ones.
"Opposition based on the hemstitching and embroidery of the law appeared petty in terms of Warren's basic-values approach," Justice Abe Fortas told the historian Bernard Schwartz, and the result was "the most profound and pervasive revolution ever achieved by substantially peaceful means".
When the economic conditions of parents and their adult children differ substantially, equalization means transfer of economic resources from one generation to the other.
The molecular mechanisms of variations in individual longevity are not well understood, even though longevity can be increased substantially by means of diverse experimental manipulations.
During the last few decades, quantitative measurement methods used in dermatological research improved substantially, providing means of relevant evaluation of skin functions and characteristics.
However, Lipworth et al (1999) reported substantially higher mean levels of pregnancy estrogens and significantly lower mean birth weights among women in Shanghai than among their counterparts in Boston.
A UK-wide population study of a similar size and including a similar number of symptoms (25 vs. the 23 in this study), found a mean of 3.7 symptoms among respondents [ 3], a substantially lower mean than our 6.0.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com