Sentence examples for substantially lower expression from inspiring English sources

PNPLA3 in humans is predominantly expressed in the liver, with substantially lower expression level in skin and adipose tissue (Huang et al., 2010).

Tex14 appears to be highly expressed in the testis and substantially lower expression or no expression was detected in the female reproductive organs indicating a more prominent role of TEX14 in the testis.

Genes encoding polygalacturonase (SlPG2a) [ 4] and β-galactosidase (SlTBG4) [ 5], involved in cell wall softening, showed substantially lower expression in purple fruit during ripening.

In keeping with previous evidence of variable expression [ 25], we found that one pig had no expression of swine leukocyte antigen 6 (SLA6), the major histocompatibility complex in pigs and two Piétrain pigs had substantially lower expression of the cyclin M3 (CCNM3) gene than the rest of the animals.

The tumors classified as zebrafish solid SRBCTs did show slightly increased expression of rag2 and lck compared with levels in the wild type but were substantially lower than expression in the leukemia-like tumors.

It is unclear how well findings in animal studies will translate to humans as studies indicate that the expression or response of glutamate receptors in human oligodendrocytes may be substantially different (lower expression levels and resistant to excitotoxicity) from those in animals (Wosik et al., 2004; Benarroch, 2009).

In four cell lines derived from human and monkey, siRNAs substantially lowered the expression of three of four test genes--by as much as 90%.

Note that in experiments with TM neurons, 10 µM choline plus 1 µM PNU-120596 were used [43], whereas in this study, the concentration of PNU-120596 was increased to 2 µM because of the substantially lower levels of expression of functional α7* nAChRs in hippocampal CA1 pyramidal neurons compared to TM neurons.

(While we can detect Saa3 in vivo, we were unable to detect it in our explant system, likely due to its substantially lower levels of expression relative to Saa1 and 2).

Examination of PGC-1α mRNA levels in several PS1r and PS1/2−/− clones by RT-qPCR analysis revealed its substantially and significantly lower expression in PS1/2−/− vs. PS1r clones (Fig. 2A).

Other groups have reported that, in breast cancer patients, monocyte-derived DCs have substantially lower level of expression of HLA-DR than do DCs isolated from control donors, leading to a reduced ability to stimulate allogenic and Flu-specific T-cell responses [ 8].