However, these approaches are quite complicated and can achieve substantially lower genomic coverage, making these technologies more suitable for validating findings than for initial discovery [30].
The coverage probabilities for these confidence intervals in the setting of autocorrelation and overdispersion was substantially lower, with actual coverage probabilities ranging from 87% to 96%.
Second, early GWAS arrays have substantially lower genome-wide coverage of common SNPs for African ancestry (28 49 %) compared to European ancestry populations (75 86 %) [ 44], leading to inefficient imputation and loss of power to detect association.
Djibouti had substantially lower measles immunization coverage in 2003 than it did in 1990, although the last few years have actually shown significant rises following a catastrophic drop to little better than 20 per cent in 1998-1999 due to a breakdown in the cold chain.
On the other hand, firms with high collective agreement coverage have a substantially lower probability of reporting external factors as the main determinant of hiring pay.1.1
The 13 L. donovani positive pools did originate from 6 neighboring wards where IRS coverage had been substantially lower (wards 1, 5, 16, 18 & 19, IRS coverage 10-70%), however the absolute numbers of infected sandflies captured were low and random variation may have played a role.
While we were unable to make village-specific estimates of sporozoite prevalence, the overall mean reported here at high bednet coverage is substantially lower than previous reports for both vector species in both villages previously surveyed.
While high-income countries have long maintained near-universal coverage of antiretroviral medicines for pregnant women, in low- and middle-income countries, coverage required to prevent mother-to-child transmission only reached 57%, with reported coverage in Asia substantially lower at just 18%.
Importantly, for the scenario (accelerated 1st dose only) and the measure (RVGE hospitalizations) that are common between our study and the Halvorson et al. study, our model yielded substantially lower reductions (274 vs. 737 2210 [depending on vaccine coverage and efficacy]).
