"substantially limit" is correct and usable in written English.
You can use it when you want to express that something restricts or reduces the ability of something to a large degree. For example, "The new tax law will substantially limit the profits of small businesses."
In this context, the widely acknowledged limitations on sensitivity and specificity of a single Pap test would substantially limit clinical effectiveness (Baldwin et al, 2003).
An impairment or diagnosis does not necessarily constitute a disability; it must substantially limit these activities.
Judges substantially limit this approach because it can be an unnecessary distraction.
Its reasoning was that such a believed capacity does not substantially limit an individual in performing major life activities.
We provide accommodations for students whose disabilities substantially limit their ability to live in CUIMC's traditional housing units.
Police officers are subject to local and departmental rules that can substantially limit what tactics are allowed.
The Justice Department's antitrust unit will aim to determine whether the deal will substantially limit consumers' choices.
Moreover, it adds, "an impairment that is episodic or in remission is a disability if it would substantially limit a major life activity when active".
Moreover, it says, "an impairment that is episodic or in remission is a disability if it would substantially limit a major life activity when active".
The courts on a number of occasions have rendered decisions that substantially limit or reduce citizens' rights.
The decision today, C.I.A. v. Sims, No. 83-1075, may substantially limit the disclosure of material that Congress itself chose not to limit.
