Sentence examples for substantially less active from inspiring English sources

Of note, the Vpu of the T cell line-adapted NL4-3 clone, which has been utilized in most previous studies, was substantially less active in reducing IKKβ-induced NF-κB activation (62.0% ± 9.5%) than the Vpu proteins of 28 other HIV-1 M strains analyzed (5.3% ± 1.3%; p < 0.0001).

It is surprising that the mutation of K220 did not completely abrogate activity, but instead resulted in a substantially less active kinase.

The human P347S hammerhead ribozyme was substantially less active (~10,000 fold).

The novel proteins are substantially less active, and may function by different mechanisms than the natural proteins they replace.

Although all 17 isolates possessing tccC were found to produce bipyramidal crystals and had previously been found toxic to lepidopteran larvae, sporulated cultures of selected tc-positive isolates were found to be substantially less active against gypsy moth larvae than was IBL 455, which was isolated from a 1980 preparation of Dipel® (Abbot Laboratories, Chicago, IL, USA).

Docetaxel metabolites are substantially less active than the parent drug; hence, CYP3A-mediated metabolism is the major route of inactivation.

Adults with intellectual disability (ID) are substantially less physically active than the general community [ 1– 3] which may contribute to preventable physical and mental health problems [ 4, 5].

Thus, after adjusting for the effect of the covariates, being a Palestinian housewife was significantly associated with a lower prevalence of insufficient activity compared to women in paid jobs, and women with university degrees were substantially less likely to be insufficiently active than women with less than high-school education.

Of these, 46 were substantially more active, and 33 were less active, in tumor endothelial cells than in those from normal colon tissue.

Interestingly, Kras/ Lkb1 tumors show substantially less phosphorylation of ERK, suggesting that the ERK pathway is less active in these cancers.

Analogous Pt0 and Ru0 sols are more active than the Au0 nanosols, but substantially less chemoselective for allylic alcohols.