Sentence examples similar to substantially laborious from inspiring English sources
However, both ZFNs and TALENs are nuclease-based designs that are difficult to construct, and the efficiency of targeting varies substantially, making these laborious approaches.
However, the definite identification of peptides/proteins underlying single biomarkers from laser-microdissected material demands substantially higher cell amounts and laborious, time-intensive procedures.
While one can efficiently isolate conditional, embryonic-lethal C. elegans mutants, positional cloning of the mutant loci has remained laborious and time consuming, substantially limiting the utility of mutant screens, particularly given how readily one can use RNA interference to probe essential C. elegans gene functions [6], [28], [29], [30], [31], [32].
At the southwest Pacific ICEMR, two new quantitative polymerase chain reaction (qPCR) assays have been developed for Plasmodium falciparum that target repetitive genomic sequences, substantially increasing diagnostic sensitivity without requiring laborious sampling of large blood volumes or elaborate sample processing.
Because this is often laborious and not straightforward, few broad-based computational phosphorylation prediction procedures have had their results substantially confirmed through experimental verification.
The requirement of laborious training procedures pose a particular challenge when developing flexible industrial applications and this issue is substantially exacerbated if new materials are often included in the classification process, a situation when retraining is necessary.
Connected prose is laborious.
It sounds incredibly laborious.
