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Steatohepatitis was confirmed in the MCDD mice, with substantially increased plasma alanine aminotransferase (Table 2) and inflammatory infiltrate in the liver on immunohistochemistry (Fig. 2).
Use of FITC-labeled anti-HA antibodies substantially increased plasma membrane 488 nm channel green fluorescence compared to samples incubated with unlabeled anti-HA.
These data suggest that the relative brain accumulation of paclitaxel was not altered by elacridar and ritonavir co-administration, despite the substantially increased plasma levels of paclitaxel and the circulating elacridar levels.
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The dose of LPS was used based on previous observations that it substantially increases plasma and lung IL-1β levels [19], and oxidizes plasma Eh Cys/CySS at 2 h [20].
In trial 1, LPS substantially increased the plasma lactate concentrations.
This indicates that neither the circulating elacridar levels, nor the increased plasma taxane levels were sufficient to substantially inhibit or saturate the taxane export activity at the BBB.
The uptake time of a water droplet can be greatly shortened and the wetted area can be substantially increased by a plasma treatment.
Here we report the surprising finding that ANA levels are substantially increased in the plasma of patients affected by CM, at the expenses of all other kynurenine metabolites with the notable exception of XA.
The plasma spray substantially increased the surface area of the implants by increasing their surface roughness [ 46].
The intensity of RFP-PH signals at the plasma membrane was substantially increased (10.4% higher) in gray scale compared with the level at 0 00, suggesting that the second phase of RFP-PH increase at the plasma membrane was temporally correlated with the elevation process of the vitelline layer.
Also consistent with previous observations, 4 CPHPC plasma exposure was substantially increased in patients with reduced CRCL, resulting in prolonged SAP depletion.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com