Repeated vaccination substantially increased the frequency of IFNγ-secreting CD8+ T cells without increasing the frequency of CD4+ regulatory T cells (data not shown).
Rag2 truncation substantially increased the frequency of off-target V(D J recombination.
Such an ability would substantially increase the frequency of engulfment and the likelihood that a stable enosymbiosis would be established.
Punishment does not substantially increase the frequency of cooperation within groups because the transmission bias is weak, so punishment cannot create an inclusive fitness benefit, and does not increase in frequency.
In most areas, using the outcome-linked diagnostic criteria in Table 1 and the detection strategy in Table 2 will substantially increase the frequency of hyperglycemic disorders in pregnancy.
Following a 4-week implantation period in a rat muscle pouch defect model, both AB and HFIP scaffolds supported in vivo adipogenesis either alone or seeded with hASCs or hMSCs as assessed by Oil-Red O analysis, however the presence of exogenous cell sources substantially increased the extent and frequency of adipogenesis observed.
The ex vivo incorporation of BMSCs into all bone-derived scaffold preparations substantially increased the mean extent and frequency of samples containing de novo bone formation over similar nonseeded controls, as determined by histological and histomorphometrical analysis.
CN V, VII, IX and X anomalies were seen occasionally in WT embryos; however, the severity and frequency was substantially increased in LgDel embryos.
An interesting observation was the increased incidence of Klinefelter's syndrome (47, XXY) in male patients with SLE, in whom the frequency was substantially increased (14-fold) compared with men without SLE, suggesting that the susceptibility to SLE could be due to an X-chromosome gene-dose effect [ 84].
A feature of the 2D data that differs from prior reports is the substantially increased time allocation over the low-frequency portion of the frequency sweeps that was shown by some rats under the influence of cocaine (e.g., Figs. 6a,9,10); this effect was greatest at the lower price.
