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When inserted in the cAMP indicator, L20 yielded a probe showing almost doubled FRET efficiency and a substantially improved dynamic range.
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In addition to substantially improved resolution, NUS can also be exploited to improve sensitivity, with gains comparable to those obtained using cryogenically cooled probes.
In the questionnaire after the intervention period, participants were asked an additional question regarding perceived improvement of coldness symptoms: "Did your symptoms of coldness improve?" for which the selectable answers were: "substantially improved", "somewhat improved", "unchanged", or "deteriorated".
For the analysis, we categorized the "substantially improved" and "somewhat improved" as improved, and "not changed" and "deteriorated" as not improved.
He said the spending plan was "substantially improved for education, for health care, for seniors, for colleges and universities, for transportation and for mental health".
As a consequence, an improved dynamic behavior may be exhibited.
Investors snapped up financial shares amid speculation that bailed-out companies were on track to report substantially improved balance sheets.
This article presents a new and substantially improved finite volume procedure for simulation of incompressible flows on non-orthogonal grids.
The introduction of novel drugs has changed the treatment of the disease and substantially improved survival outcomes.
The WL-MLEM algorithm with wobbling PET yielded substantially improved resolution compared with conventional algorithms with stationary PET.
Deeper understanding and substantially improved analysis of the laser shot backscatter of natural objects by having direct access to full-waveform signatures and physical observables are expected.
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