Thus, the complete conservation at HA1 190 and the nearly complete conservation at HA1 225 were consistent to the importance of these residues in allowing for binding to human-like α(2,6) receptors [40], [41], supporting the substantially higher human-to-human transmissibility of the 2009 A(H1N1) virus than seasonal A(H1N1) viruses [5], [8].
Previous evidence showed that market closures are highly effective in preventing H7N9 virus infections in humans (10, 11 ) by substantially reducing human exposure to poultry.
This is in contrast to a recent paper where shRNA-mediated repression of FZD7 decreased POU5F1 expression substantially in human ES cells and moderately in the human EC cell line NCCIT [ 47].
Summary: Copy number variants (CNVs) contribute substantially to human genomic diversity, and development of accurate and efficient methods for CNV genotyping is a central problem in exploring human genotype phenotype associations.
The two approaches were equally accurate about half of the time, but the data-based diagnoses substantially outperformed human judgment in nearly half of the studies.
Access improvement measures substantially reduced human impact and dune vulnerability.
We present experimental results demonstrating that teaching guidance substantially improves human teaching in three different problem domains.
After becoming president in 1986 Yoweri Museveni introduced democratic reforms and was credited with substantially improving human rights, notably by reducing abuses by the army and the police.
The impact and resulting fires may have triggered mass wasting events as well as significant changes in erosion rates and have substantially affected human uses of the area.
Although recent efforts taken have substantially contained human onchocerciasis in many African countries, published reports indicate a recrudescence of the disease.
