Sentence examples for substantially hindered from inspiring English sources

However, therapeutic application of CA4 is substantially hindered due to geometric isomerization.

The presence of Laponite particles substantially hindered the release of a number of proteins that otherwise showed burst release from these hydrogels.

The use of the superplastic forming in high production applications has been substantially hindered by the process required long cycle times.

Heparin competes with IP3, but its access to the IP3-binding core is substantially hindered by additional IP3R residues.

Repair of SSBs and DSBs was most rapid during S then G2 phases and was substantially hindered by rucaparib.

In addition, since fatigue substantially hindered patients' ability to perform their daily activities, the management of fatigue could potentially improve overall HRQoL.

Undetected or ill-mapped geologic hazards can stop or substantially hinder project development with respect to profit and safety.

However, their low transfection efficiency substantially hinders their application in both clinical practices and academic research, which is mostly attributable to the low capacity of siRNA/cationic macromolecule complexes to escape lysosomes.

The contorted polymer chain forms a very stable morphology and substantially hinders interactions between chromophores, thus diminishing the formation of aggregated species that are commonly observed in other electrooptically active polymers.

Weak or failed monsoons (droughts) result in widespread agricultural losses and substantially hinder overall economic growth.

However, the generation of very high affinity antibodies has proven to be difficult to some promising tumour targets, thus substantially hindering their use for cancer treatment.