Notably, the averaged density of Nrd1 and Nab3 hits over all annotated CUTs was substantially higher than over annotated SUTs, ORFs or intergenic regions in each of the high-throughput data sets.
The finding that the averaged density of Nrd1 and Nab3 hits over all annotated CUTs (Xu et al, 2009) was substantially higher than over annotated SUTs, ORFs or intergenic regions in each of the high-throughput data sets, strongly supports the idea that Nrd1 Nab3 binding constitutes one general feature that targets ncRNAs to the exosome.
In agreement, we noted substantially higher (from 6 to over 200 fold) expression of the former group of genes and lower (3 18 fold) expression of the latter group in our dataset.
For all the eight active histone modifications (we examined the subnuclear localizations of five of them as described above), less than 5% of the ChIP-seq peaks are within the sLADs and the peak densities in non-sLADs are substantially higher (about 10 to over 200 folds) than those in sLADs.
Compared to previous designs, the Helmholtz pair provides substantially higher B1 homogeneity over an extended volume of interest sufficiently large to image biologically relevant specimens.
Among females aged 15 18 years, the overall weighted prevalence of HPV was substantially higher (15%); over 80% were infected with high-risk types and almost half of all infections were with types 16 and 18.
However, a recent study comparing the siblings of unipolar depressives with the siblings of healthy controls using strict definitions of both depression and health found a substantially higher λs of over 9 [ 4].
Several studies that estimated potential savings among patients initially with moderate AD reported substantially higher cost saving over time, ranging from US$2533 to US$4995 (Getsios et al 2001; Garfield et al 2002).
Another randomized trial [ 65] of approximately 132,000 women, aged 30 59, conducted over 7 years in rural India also reported substantially higher sensitivity of HCII over cytology.
They find that black individuals have substantially higher levels of unemployment over their work careers than their white counterparts, and show further that much of this gap remains after accounting for racial differences in cognitive skills as measured by the AFQT.
