It is worth noting that CFRP confinement increased the axial resistance of the unheated column by about 40% whereas the same wrapping system induced substantially higher effects when used to confine heat-damaged columns.
The five SNPs on chromosome 4 that were detected in the filtered but not the complete inbred panel had substantially higher allele effect estimates in the filtered panel, but similar allele frequencies across panels (Table S1 in Additional file 1).
In contrast, with the substantially higher placebo effect (-33.2%) observed in patients (n = 231) from the Eastern Europe/Russia study site cluster (Fig. 3), neither SPN-804 dosage group was significantly superior to placebo (1200 mg: −38.4%, P = 0.60; 2400 mg: −41.2%, P = 0.13) in this subset.
As Figure 1 shows, the quantile effects of the number of CPC measures reported was less than the mean effect in the lower tail of the VBP score distribution; however, the effect was substantially higher than the mean effects in the upper tail.
The GE variation of lymphoblastoid cell lines, which are important materials for dissecting genetic basis of GE variation of human populations [ 23, 26, 27, 35, 36, 45], reflects a substantially higher proportion of genetic effect compared to the effect of food preferences or environmental exposures [ 46].
The death toll from air pollution, usually put at around 29,000 a year in the UK, could be substantially higher because the lethal effect of nitrogen dioxide (NO2), emitted during fossil fuel burning, has not been taken into account, experts believe.
These changes are substantially higher than the retest effects in the comparable sample without training.
When both random effects were included together in a null model, the variance of the farm random effect (0.6) was substantially higher than the variance of the house random effect (1.4 × 10-15).
All these factors mean that it is difficult to extrapolate relevant in vivo concentrations of toxicants from in vitro results alone, and typically, the concentrations required for a given effect in vitro will be substantially higher than those required for parallel effects in vivo (Coecke et al. 2007).
