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As discussed in the preceding section, however, adult worms pose a substantially greater challenge for cellular annotation than L1 worms.
By using a much smaller set of landscape metrics (nine vs. 92), we dramatically reduce the amount of information available for distinguishing landscapes, providing a substantially greater challenge for the clustering algorithm.
"Without that, the challenge would be substantially greater," he added.
Nevertheless, management of gout in diabetic patients presents a challenge because of the substantially greater prevalence of each co-morbidity in patients with gout or with diabetes compared with non-gouty and non-diabetic individuals 11, 12.
FOR the people in charge of Mr. Romney's national election night event in Boston, the challenges are similar but the stakes substantially greater and the margin for error lower.
We also consider evidence that the resistance seen in wild-type p53 cancers can be substantially greater than that seen in mutant p53 cancers, and this poses a far greater challenge for efforts to design strategies that increase drug response in resistant cancers already primed with wild-type p53.
Although both pose challenges, a product with a shelf life of only two days poses substantially greater logistical issues than a product that remains stable for a week.
The cost will be substantially greater".
But other experts say the savings could be substantially greater.
But it has overcome greater challenges before.
A college degree still leads to substantially greater lifetime earnings.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com