Sentence examples for substantially given that from inspiring English sources

The two BEST algorithms, i.e., BEST-slope and BEST-intercept, differed substantially given that 19 and 76 runs out of 80 were successful in the former and the latter case, respectively, and only BEST-intercept was usable for low steady state infiltration rates (is < 0.038 mm s− 1).

The costs could rise substantially given that a federal lawsuit may require the state to spend $8 billion to bring the prison system's woefully inadequate medical services up to constitutional standards.

We did not find it necessary to expand the Methods section substantially given that the employed methods are well described in the literature.

Use of a different study (eg, ARISTOTLE) for baseline event rate data is unlikely to change the results substantially, given that the event rates in standard adjusted dose VKA arms were similar across studies.

Such assumptions probably did not influence our conclusions substantially, given that rapid replacement was predicted to occur for all assumptions about contact between individuals in the model population, if the vaccination coverage was in a realistic range (i.e. ≥40%) and if the importation rate was about 3 cases per million per year.

Although the disease status was unknown for the 1000 genomes and NHLBI control cohorts, contamination of controls with undiagnosed cases is unlikely to influence the results substantially given that Paget's disease is a relatively uncommon condition occurring in about 1% or less of the European populations.

However, these differences are negligible given that WGCNA* substantially reduced the number of markers needed for validation.

For example, we now state: "Given that NMD substantially reduces the levels of ttna transcripts with premature termination codons, we reasoned that we should be able to distinguish N- and C-terminal truncation mutants by the ratio of Cronos to full-length transcript.

DOI: http://dx.doi.org/10.7554/eLife.09406.013 Given that NMD substantially reduces the levels of ttna transcripts with premature termination codons, we reasoned that we should be able to distinguish N- and C-terminal truncation mutants by the ratio of Cronos to full-length transcript.

Given that NADH binds substantially more tightly to SNF1 than AXPs, and given the relative concentrations of AXPs and NADH in yeast (Canelas et al., 2008), we conclude that under most conditions this site will be occupied by NADH.

Given that familiar food substantially increased ADF activity compared to the baseline, at least two neural pathways should act antagonistically in controlling the activity of ADF or its upstream neurons.