Sentence examples for substantially directed from inspiring English sources

The CM79 site, a surface-exposed conformational B-cell epitope comprising the C-terminus and an internal sequence of CP has been identified by this method and we have shown previously that the human antibody response to CP is substantially directed towards this CM79 site.

The strong sequence diversity demonstrated here suggests that instead phosphite oxidation is likely an old activity, and the very similar catalytic parameters, combined with the inability to increase kcat substantially by directed evolution, suggest that the rates of oxidation of phosphite by PTDHs may be limited by a relatively high intrinsic barrier.

Participant time contributed substantially to direct nonmedical costs.

In rural areas, travel and food costs contributed substantially to direct patient costs; this finding is similar to those of other studies reporting such costs to be the greatest barriers to obtaining health services (Ensor and Cooper 2004; Peters et al. 2008).

In addition the mean flow velocities are comparable, yielding a substantially larger offshore directed sediment transport capacity.

Toxic effects of anti-CD22 therapeutics are thus directed substantially against the mature B-cell pool, reducing myelotoxicity.

10 Private transfers, including education, bequests, and a range of others, substantially offset public funds directed towards older people.

Medications suggested or prescribed by the dentist will help manage pain and swelling substantially if taken as directed.

Arab investments in Egypt slipped to $1.58 billion in 2010 from $1.7 billion in 2009, substantially less than the $2.27 billion directed by Egyptian investors into other Arab countries, according to the report.

The risk of hypoglycemia is seen primarily in patients treated with insulin or insulin secretagogues, and it increases substantially when pharmacologic therapy is directed towards maintaining the glycemic concentrations as close to those found in nondiabetic individuals as is safely possible (44, 46).

So Spanish sophisticated households hold substantially more direct stock but substantially less indirect one.