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The hypervariable region(s) chosen for amplification can influence the PCR-DGGE profiles and diversity indices produced from community DNA samples, and even subtle differences in primer sequences can result in substantially different profiles and downstream assessments of microbial diversity.
A value of k = 6 was chosen as data elimination (25%%) revealed profile stability while k values greater than six did not produce substantially different profiles.
It is uncertain whether their results can be extrapolated to East Asian diabetic subjects, who have substantially different profiles regarding CHD and its risk factors, including a much lower incidence of CHD and degree of obesity (20– 20).
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In contrast, RNA-seq analysis reveals substantially different expression profiles.
Through the use of Next Generation Sequencing technology we have demonstrated that both epididymal epithelial cells and spermatozoa harbour a complex repertoire of miRNAs that have substantially different expression profiles along the length of the tract.
In contrast to our model study, for this field data-set, the MT and quasi-electric tensors are quite different, most probably due to substantially different conductivity profiles below the field and base site, as 3-D inversion revealed (Samrock et al. 2015).
Data generated in this manner indicated that mice from the Manchester breeding house had substantially different GTM profiles from C3H mice at Stanford University (c. 60% concordance for Manchester vs. Stanford compared to >80% inter-strain concordance; Figure 6) despite being nominally identical strains.
However, they provided substantially different protein profiles.
Docetaxel and paclitaxel also have substantially different toxicity profiles.
These two sectors present substantially different risk profiles with respect to CT utilisation.
As expected, owing to their very distinct biology, MCF7 and SUM159 had substantially different genomic profiles.
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