Sentence examples for substantially different outcomes from inspiring English sources

Several studies have examined the relative contributions of patient characteristics to survival and have attempted to identify subgroups of patients with substantially different outcomes in order to tailor therapy and to influence the design, stratification and interpretation of future clinical trials.

Molecular features are associated with substantially different outcomes [ 4] and with wide variability in response to standard therapies [ 5, 6].

The current lack of standardization in the design, analysis and reporting of results from economic evaluations, and substantially different outcomes [ 54], also lead to a lack of comparability.

Identification of patient subgroups with substantially different outcomes is therefore necessary to tailor therapy and to help with the design, stratification and interpretation of future clinical trials.

The exact timing of HRQoL assessments is important for the interpretation of the results (immediate effects versus long-term effects), and modest changes in the timing of an assessment can result in substantially different outcomes.

Recent studies have examined the influence of patient characteristics on survival in this setting and have attempted to identify subgroups of patients with substantially different outcomes in order to tailor therapy and to rationalize the design, stratification and interpretation of clinical trials [ 13- 19].

It should be realized, however, that some predictions are potentially more informative, especially those which are designed to test if highly similar conditions of novel stress (e.g. in replicated experiments) can result in substantially different adaptive outcomes.

Of course, some evaluations are potentially more informative, especially those which are designed to test if coping with similar conditions of novel stress (e.g. in replicated experiments) can result in substantially different adaptive outcomes.

Model 1, without adjustment, compared to model 2, with adjustment, produced substantially different HSMR outcomes.

A model without this adjustment, as opposed to a model with the adjustment, produced substantially different HSMR outcomes.

These results were not substantially different when outcomes at 60-64 years only were used, i.e. without conditioning these on their corresponding age 53 scores (data not shown).