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The results of this analysis are also similar to those of Solberg et al. [ 44] in the USA who estimated an ICER of $1755 (equivalent to €1721 in 2008 prices) and Tariq et al. [ 45] in the Netherlands who estimated an ICER of €5400, although these studies both use substantially different methodologies.
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For example, for rapid on-site analysis for the purpose of directing a site remediation project, a substantially different methodology can be used compared to that required for legal action.
This is substantially different from methodologies that depend on database screening to get new drug candidates.
There is one randomized controlled trial [25, 26] that showed benefit of FETO; however, in that study all deliveries were by EXIT procedure, there was a case mix of right and left CDH, and the methodology was substantially different to what is currently being practiced in Europe and the USA.
Other reports that employ different methodologies find a substantially larger amount of work among program recipients.
Population enrichment provides additional improvement over item optimization alone [ 5], but optimizing within an enriched population does not result in substantially different item combinations, indicating that the methodology successfully identifies the disease-specific decline across homogeneous or heterogeneous MCI patient populations.
It is important to be clear about the objectives of dioxin/furan/DLPCBs determinations, because there are several choices in methodology associated with substantially different costs that generate data of differing precision and accuracy [ 54].
Because the results for these comparisons were not substantially different we elected to report the results using conditional logistic regression as it was the originally proposed methodology for the study.
Different methodologies will produce somewhat different results.
(Substantially different 2004 working paper).
There are different methodologies for getting there".
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