Consequently, drug costs differed substantially between continuous and discontinuous treatments (table 1; p<0.001), as well as between ranibizumab and bevacizumab (p<0.001).
In effect, we were comparing these standards with a schedule that much more substantially reduced continuous working hours than the ACGME regulations demand, with a maximum of 16 scheduled consecutive hours.
The cycle superhighway will be made up of two routes, one going three miles north-south from King's Cross to Elephant and Castle and the other travelling 18 miles east-west from Barking to Acton – making the biggest continuous, substantially segregated urban cycleway in Europe.
Hydraulic, sanitary, and sulfide control conditions of inverted siphons, particularly in large wastewater systems, can be substantially improved by continuous air injection in the base of the inclined rising branch.
Results did not substantially differ when continuous variables in the final model were categorized into dichotomous variables.
Because the reading of displays by the driver in an automobile is limited to brief glances, reading in this environment is substantially different from continuous or immersive reading considered in typical legibility studies.
We recently argued that currently used markers of systemic inflammation such as C-reactive protein and procalcitonin are substantially cleared during continuous renal replacement therapy (CRRT) and thus may lose sensitivity to evaluate the degree and evolution of inflammation [ 2].
This professional attitude has substantially contributed to a continuous supply of medicines from the Ministry of Health throughout the country, of particular benefit to those living in hard-to-reach rural areas.
In the presence of R115777, however, the systemic exposure to total drug levels of irinotecan and its metabolite SN-38 was substantially increased, especially following continuous administration of R115777.
