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Especially in dynamic studies, in single gates of a respiratory-gated study, and in scans of obese patients SNR can be very low initially and a good SNR can only be obtained by substantially compromising spatial resolution.
We also show that the number of medial sheets comprising this representation may be significantly reduced without substantially compromising the quality of the reconstruction, to create a more useful part-based representation.
The ability to make conclusions on the correlative studies becomes underpowered, substantially compromising the risk benefit of performing these procedures.
Previous methodological studies suggested that the number of items in some scales can be reduced by about 70% without substantially compromising the measurement properties [ 16- 18].
The results of the implemented measures shows that the reduction potential identified by a LCA-analysis and implemented into daily business can lower the overall impact without substantially compromising the company economically.
The use of AG probes reduced the number of probes included on the chip for background correction by 99% compared to the use of mismatch probes (allocated to half of the array positions in pre-vious designs), without substantially compromising the ability to perform accurate background correction [ 19].
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In Zambia, intensive training in a task shifted model of ART rollout was able to expand treatment access substantially without compromising quality of care [ 39].
Given that the prevalence of this infection often exceeds 20% in high-risk populations, this approach can reduce costs substantially without compromising the accuracy of the tests.
In some cases, this is a small core that becomes ischemic due to loss of blood flow and is surrounded by a "penumbra" of tissue where local blood flow is substantially reduced, compromising neuronal function but not viability.
In motor neurons of γ-synuclein transgenic mice, the level of HSP25, a mouse ortholog of HSPB1, is substantially reduced, potentially compromising the survival of these cells.
Overall, these data support the use of combination therapy with EVE+EXE to substantially improve PFS without compromising QOL, thereby achieving an important goal in the management of advanced BC.
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