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Unfortunately, solid malignancies, such as bone sarcomas and cystic soft-tissue sarcomas, may respond well to chemotherapy without substantially changing in size.
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With so much momentum to overcome, lobbyists and corporate executives are not holding out much hope of substantially changing much in the accounting and corporate-governance overhaul legislation on Capitol Hill.
It is well known that two distinct structures with similar energy can easily exchange their rank order with respect to energy without substantially changing their relative frequency in the ensemble.
Second, in some cases such as cancer, mutation of miRNA sequences may cause activity changes without substantially changing the expression levels.
Regularities substantially changing the existing concept of transfer processes in the interfin space and in the wake behind a finned tube are revealed.
With the end of the Cold War, the probability of a ground invasion of Switzerland ended, substantially changing Swiss military doctrine and resulting in reduction of both the budget and the size of the Swiss Armed Forces.
Our T18 and T24 data suggested that the heat pulse could be up to 12 hr in length without substantially changing phase-shifting behavior.
Such belief in the possibility of substantially changing social and political realities is at the heart of both pragmatism and feminism.
Excluding trial data obtained only in abstract form reduced heterogeneity without substantially changing the effect estimate (Additional file 1: Table S7d).
This association remained in the multivariate model at week 52, without substantially changing the other associations (AOR 0.08 95%% CI 0.02, 0.27).
NGS offers the promise of tremendous public benefit as it underpins both improvements in our understanding of disease as well as substantially changing our practical ability to translate this knowledge through improved diagnostics and therapeutics.
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CEO of Professional Science Editing for Scientists @ prosciediting.com