Sentence examples for substantially blunted from inspiring English sources
But their report, released here on Friday by the Intergovernmental Panel on Climate Change, said warming and its harmful consequences could be substantially blunted by prompt action.
Bernardin and colleagues [ 13] observed that, in PBMCs of patients with severe sepsis, production of isoprenaline-, Nand, and forskolin-induced cAMP was each substantially blunted, suggesting heterologous desensitization of the β-adrenergic pathway with defects at the level of AC.
Combined inhibition of nitric oxide and prostaglandins augments sympathetic α-adrenergic vasoconstriction, yet the vasoconstrictor responses were substantially blunted compared with resting conditions, indicating that other signals compensate to maintain blood flow to the contracting muscle (4).
Most highly trained athletes (including a large portion of the cohort of athletes studied in our laboratory) display substantially blunted peripheral chemoresponsiveness with HVR values that are quite homogeneous.
That is, the tight regulation of ER-α appears to be diminished in mammary tumors compared with normal mammary tissue in that its ligand-mediated down-regulation is lost or at least substantially blunted.
We find that expression of the DN-DaPKC is sufficient to substantially blunt the elevation in Upd levels as measured by immunoblotting for total Upd protein present in ept/M 3) eye-antennal discs (Fig. 4G).
Treatment of forskolin substantially blunts this effect (to 17.3 ± 4.8%; Figure 5A), confirming that the Gpr52's effect is mainly mediated via the cAMP-dependent Htt reduction.
Those blunted dopamine receptor variants are associated with substantially increased risk of addiction to a range of substances and behaviors.
Importantly, this event was substantially reduced in CM-treated cells, suggesting that CM blunted LPA-induced signalling at a very early step.
This observational study suggests that dexmedetomidine therapy for severe alcohol withdrawal is associated with substantially reduced benzodiazepine dosing, a decrease in alcohol withdrawal scoring and blunted hyperadrenergic cardiovascular response to ethanol abstinence.
