"substantially based on" is a correct phrase and can be used in written English.
It is typically used to indicate that something is largely influenced or derived from something else. Example: The company's new product is substantially based on customer feedback and market research.
Long-term budget forecasts are notoriously unreliable, and the fiscal outlook could change substantially based on how the economy performs.
Where there's a will, there is, indeed, a way: a meme now circulating throughout the denialosphere is that the IPCC's conclusions about regional warmth contradict our findings, despite the fact that those conclusions are substantially based on our findings.
The work of these engineers was substantially based on pioneering research and development by a team of British engineers and scientists at the National Physical Laboratory, a government R&D establishment, under its leader Donald Davies.
The reputation the second century won as a golden age was substantially based on the unusual stability of the political establishment during this period and on the economic prosperity that helped to nurture.
Janine Gordon, who is known as JahJah and is also a musician and multimedia artist, has filed suit against Mr. McGinley in federal court in Manhattan, saying that at least 150 of his photographs are "substantially based" on her work and are violations of her copyright protections.
In July, Janine Gordon, who is known as JahJah and is also a musician and multimedia artist, sued Mr. McGinley — who is best known for his artfully constructed visions of young men and women — claiming that at least 150 of his photographs were "substantially based" on her own and were violations of her copyright.
The subject of process and plant technology substantially bases on the dynamic behaviour of chemical processes.
But it seems unlikely that bird flu surveillance and control programs will be substantially changed based on this research.
The inhibition efficiency of the inhibitors is substantially defined based on their adsorption properties.
Costs among etanercept patients did not substantially differ based on dose escalation ($14,482 vs. $13,866 respectively).
The total prevalence of pathologic glucose metabolism was substantially higher based on HbA1c values than based on OGTT.
