Sentence examples for substantial uptake of from inspiring English sources
The biodistribution data showed substantial uptake of 7.1 ± 0.12 (%ID/g ± SD) in the brain at 5 min post-injection.
On the other hand, the SPECT images revealed a substantial uptake of 111In-RGD-MSAP in other regions of the mouse, e.g. the liver and kidneys, a finding that correlates with previously reported biodistribution studies [30].
The USEP-exposed Jurkat (A) were positive for PS externalization without substantial uptake of Pr, thus agreeing with previous publications [26], [39].
Under normal circumstances, a substantial uptake of the aforementioned radio tracers is noted in the brain and cerebellum (Fig 1).
In 2005, Chambliss and Brooks were part of the first team to document substantial uptake of pharmaceuticals in fish, and experts agree their latest findings are consistent with the work conducted to date by a number of scientists.
Furthermore, leptin-treated cells showed a substantial uptake of the serum carrier proteins albumin and alpha-2-HS-glycoprotein. Conclusions: This screening reveals that leptin influences the levels of key proteins involved in breast cancer which opens new avenues for the study of the molecular mechanisms linking obesity to breast cancer.
We finally provide a list of suggestions for strategies to obtain substantial uptake and transport of drug carriers at the BBB with a concomitant transport of therapeutics into the brain.
In previous animal studies of our 64Cu-labelled chelators (without a targeting vector), substantial uptake and retention of activity was observed in the kidneys by small-animal PET imaging (Gotzmann et al. 2016).
In addition, when participants wore hoods, the total uptakes of DEP and DnBP estimated from urinary metabolite levels corrected for background and hood air uptakes and normalized by air concentrations as well as both air concentrations and body weight (see Supplemental Material, Figure S4 indicate substantial dermal uptake of DEP and DnBP directly from chamber air.
For example, partial volume effects (PVEs) can mask substantial uptake variations in small lesions.
In several cases, substantial uptake differences were observed within subject: In 13/16, subjects' primary tumour uptake was higher than or similar to that of metastatic nodes, whereas in 3 subjects (patients 2, 10 and 16), nodal uptake was greater than the primary tumour.
