Sentence examples for substantial trials from inspiring English sources

A few years later, he asked William Chesser, a childhood friend with a background in education issues, to help him design more substantial trials.

The 2013 Cochrane Review of smoking cessation interventions for those younger than 20 years identified 28 substantial trials, of which only 3 were statistically significant [ 3].

It is also recognised that there will be a need in the future for more substantial trials to demonstrate a) the effectiveness of health literacy needs assessment and response planning as a means for agencies to improve outcomes in relation to identified limitations to equity and effectiveness; and b) the utility of many of the specific intervention ideas.

Although observational studies might suggest a simplistic hypothesis for high density lipoprotein cholesterol, that increasing the levels pharmacologically would generally reduce cardiovascular events, in the current era of widespread use of statins in dyslipidaemia, substantial trials of these three agents do not support this concept.

Finally, the process of optimization is not necessarily efficient and may entail substantial trial and error.

Instead, current methods to develop robot control code still require a substantial trial-and-error component to the software design process.

There has been substantial trial-and-error research based upon installations of sand fences, but only limited research on the fence and site attributes that provide the main aerodynamic and morphodynamic controls of interactions between aeolian systems and the fences.

There are substantial trial data indicating fairly predictable lipid-modifying efficacy for each statin.

Due to substantial trial heterogeneity an adequately powered, high quality, multi-centre randomized controlled trial is needed.

Although VA outcomes were similar to those of the MARINA and ANCHOR trials with fewer intravitreal injections, substantial trial design differences limit comparisons.

These results suggest that despite strict protocols, ample site training, and substantial trial monitoring significant heterogeneity should be expected among AD trial populations across geographic regions.