Sentence examples for substantial tissue damage from inspiring English sources

These clots frequently break off into the circulation, where they may form emboli that can block arterial beds, thus causing substantial tissue damage.

There is evidence that very strenuous physical exercise can cause substantial tissue damage and initiate an inflammatory reaction and excessive immunosuppression, in a way that highly resembles features observed in clinical sepsis [49].

As complement binding can account for substantial tissue damage in a wide variety of autoimmune/immune complex mediated syndromes such as systemic lupus erythematosus and vasculitis, inhibition of the complement system by peptides is likely to be desirable therapeutic intervention in these cases [55].

This may indicate substantial tissue damage during the 4 hour exposure at 44.5°C.

This phenomenon is thought to account for substantial tissue damage in AMD [ 41].

Host cell invasion by the gastrointestinal pathogen C. jejuni has been reported to cause substantial tissue damage, but the molecular mechanisms involved remained widely unknown.

Based on the significant tissue damage and edema observed in the cerebellum prepared after a 30 min PMI relative to a PMI of <0.5 or 2 min, one might expect a substantial increase in the levels of aggregated proteins.

The reporting radiologist should be aware of the substantial secondary tissue damage caused by in-driven fragments of bone and teeth, which themselves become secondary projectiles (Figs. 12a c and 13a, b).

Furthermore, measurement of renal function using serum creatinine is often inadequate because substantial renal tissue damage can occur before function is impaired to a detectable extent [ 4].

Indeed, the recruitment of macrophages and granulocytes (neutrophils and eosinophils) in the peribronchovascular region can cause substantial lung tissue damage due to the release of reactive oxygen species and toxic granule proteins.

Severe TBI not only causes substantial direct tissue damage, but also instantaneously breaks down existing biological barriers, generating massive pathological responses (e.g., metabolic changes) to toxic molecules and cellular debris.