Sentence examples for substantial that they from inspiring English sources

Not only is the acting of Nichols and May so substantial that they can construct believable characters out of literary rubble like that, but their literary discipline is substantial enough for them to know when a character is so solidly built that he can deliver a punch line.

Our epigenome-wide association study indicates that differences between men and women are so substantial that they should be considered in design and analyses of future studies.

Based on our results, reliable assessment of one of the culprits in AD namely HP-tau containing lesions in an interlaboratory setting can be reached when the instructions are simple and clear, the IHC labeling is robust and the lesions are substantial, that is, they have spread to isocortical structures.

We wanted to make something substantial that would last.

"They were mapped out as possible therapies in 1975 in a laboratory in Cambridge, but it was only in the late 1990s and this century that they become substantial medicines.

Viewer reaction to the clip was substantial enough that they put out another and another.

These days, some makers offer substantial differences that they assume women want: more insulation for cold feet, wider hip space and less room in the shoulders for drafts.

By the time the federal courts considered the two men's challenges to their state court convictions, there was substantial evidence that they were mentally incompetent.

For the plaintiffs, who lost hundreds of millions of dollars they invested with the Baptist foundation, there is substantial doubt that they will be able to collect much money even if they do obtain a large verdict.

The market was so hot last year that there were many sales, and some of them had increased their prices by such substantial amounts that they did not rent at all.

One reason that so many Democratic candidates so often fail to say much of anything substantial is that they prefer, instead, to wait for their Republican opponents to say something execrable.