Sentence examples for substantial targeted from inspiring English sources

"Our proposals and substantial targeted investment will make rail travel more attractive and support growth in passenger numbers by increasing seating capacity".

Soon Mohammad Hafeez was driving Rashid into the stands at long-on and a substantial target seemed on the horizon.

"It's definitely in the countries which have substantial increase in consumption – countries like China and India, which are still substantial targets for illegal imports of e-waste," he said.

Joe Root's inside edge then cannoned into the stumps to give Hasan Ali the first of four wickets and when Morgan drove a full toss gently back to Wasim, England were faltering at 92 for 3. Roy accepted the burden of ensuring a substantial target alongside Stokes, who was initially as wary as an accountant.

In this work a workflow for the generation of substantial target-oriented mechanistic process models is presented.

Towards the design of new class of podophyllotoxin to target topoisomerase II and tubulin as substantial target in cancer therapy, a series of isoxazolidine podophyllotoxin derivatives were designed.

The main goal of early phase drug development is the demonstration of substantial target engagement at doses which are safe and tolerable and the determination of a therapeutic dose range.

Once again, these can be substantial targets or they can be more readily reachable objectives like volunteering at a food bank.

Thus, as previously suggested [42], PKCγ in the dorsal horn could be a substantial target for preventing the development of tactile allodynia in the clinical setting.

These data indicated that noradrenalin neuron was a substantial target of icv nesfatin-1 in the NTS.

Lung constituents such as AECs and endothelial cells are assumed to be substantial targets in BLM-induced apoptosis in vivo [ 13, 36].