Sentence examples for substantial target from inspiring English sources

Soon Mohammad Hafeez was driving Rashid into the stands at long-on and a substantial target seemed on the horizon.

Joe Root's inside edge then cannoned into the stumps to give Hasan Ali the first of four wickets and when Morgan drove a full toss gently back to Wasim, England were faltering at 92 for 3. Roy accepted the burden of ensuring a substantial target alongside Stokes, who was initially as wary as an accountant.

Towards the design of new class of podophyllotoxin to target topoisomerase II and tubulin as substantial target in cancer therapy, a series of isoxazolidine podophyllotoxin derivatives were designed.

The main goal of early phase drug development is the demonstration of substantial target engagement at doses which are safe and tolerable and the determination of a therapeutic dose range.

Thus, as previously suggested [42], PKCγ in the dorsal horn could be a substantial target for preventing the development of tactile allodynia in the clinical setting.

These data indicated that noradrenalin neuron was a substantial target of icv nesfatin-1 in the NTS.

"It's definitely in the countries which have substantial increase in consumption – countries like China and India, which are still substantial targets for illegal imports of e-waste," he said.

In this work a workflow for the generation of substantial target-oriented mechanistic process models is presented.

Once again, these can be substantial targets or they can be more readily reachable objectives like volunteering at a food bank.

Lung constituents such as AECs and endothelial cells are assumed to be substantial targets in BLM-induced apoptosis in vivo [ 13, 36].

Such studies may also usefully consider the roles in disease of human-specific genes or isoforms (e.g. Nahon 2003; Kitano et al. 2004), as these may provide more substantial targets than SNPs or amino acids for both dysregulation and selection.