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Substantial studies have shown risk factors associated with clinical outcomes of patients who have initially shockable rhythms [ 1, 4], while less attention has been paid to initially nonshockable rhythms, such as pulseless electrical activity (PEA) and asystole [ 5].
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However, the degree of misclassification may not be substantial because multiple studies have shown the ICD-9-CM code 008.45 to be a relatively accurate way to identify CDI (24 – 24 ).
Conversely, a substantial number of studies have shown that GM-CSF fusions with foreign antigens act as immunogenic vaccines and can be used to augment immune responses against foreign antigens., Taken together, these studies suggest that the antigenic domain aside from the GM-CSF domain may bias the inherent activity of the vaccine.
Finally, a substantial number of studies have shown that there is often a weak association between high scores on process quality measures for given conditions (eg, acute myocardial infarction, heart failure) and health outcomes that matter most to patients and payers.
A substantial number of studies have shown that PAT is a source of, predominantly proinflammatory, cytokines and chemokines [ 1, 9, 31], Mazurek et al. [ 1] found that epicardial PAT from 42 patients who underwent elective coronary artery bypass graft surgery excreted higher amounts of IL-1β, IL-6, IL-6sR, and TNF-α than subcutaneous adipose tissue from these same patients.
The effect of dual WM tasks on non-verbal reasoning measures itself is a matter of substantial controversy as different studies have shown different results, and the reasons for the differences remain unclear [Jaeggi et al., 2008; Melby-Lervåg and Hulme, 2012; Redick et al., 2013].
Though a simple Poisson distribution model p(x; λ), characterized by the variance equal to the mean, can effectively handle substantial zero counts, many studies have shown that RNA-seq counts exhibit a greater variance across biological replicates than expected (Di et al. 2011; McCarthy et al. 2012).
Some studies have shown substantial gains in reading and math skills in the early grades, while others have shown more modest improvement; almost all, however, have demonstrated that Core Knowledge students do much better than others on tests of content knowledge.
However, recent studies have shown substantial improvement in CD4 counts and decreased mortality among HIV-infected patients who received ART during TB treatment compared to HIV-infected patients without access to antiretrovirals [5], [6].
Recent studies have shown substantial differences obtaining differentially expressed genes.
Previous studies have shown substantial variations in the prevalence of developmental delay.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com