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Notwithstanding these similarities, there are substantial structural differences between ATRXDBM and RASSF1CDBM.
Moreover, these kinetic differences reveal that the active sites of bacterial GluRSs and mammalian cytoplasmic GluRSs have substantial structural differences that could be further exploited for the design of better inhibitors specific for bacterial GluRSs, promising targets for antimicrobial therapy.
These observations lead us to conclude that there are substantial structural differences in the fundamental patterns of social connectivity among politically left- and right-leaning Twitter users, a finding supported by the seminal work of Adamic and Glance [34] on the connectivity patterns of high-profile partisan bloggers.
Up to date, there is no evidence showing that a pathological point mutation may cause substantial structural differences in the PrP fold.
Comparisons with the CRDs of muscle-specific kinase (MuSk) and Smo showed more substantial structural differences with an average r.m.s.
There are substantial structural differences in helices 2, but fewer elsewhere, in the cases where there are both ligand-free and ligand-bound crystal structures of lipoxygenases.
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Despite this substantial structural difference we conclude that the primary homology [ 37] of the sutured pelvis of P. robusta and pleurodires is unproblematic, because a transition from one state to the other is feasible.
The substantial structural divergence between F3H-B2 and that of three F3H-1 homoeologues is accompanied by a functional difference.
There are substantial structural and compositional differences between the two regions.
There are substantial structural and compositional differences between the two regions under consideration.
Indeed, there is substantial interest in the structural differences between human and murine apoA-I and it is plausible that they would differ in their anti-atherogenic effects.
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