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This methodology represents a substantial step forward in the approach for developing representative PM2.5 concentration datasets to correlate with inpatient hospitalizations and emergency room visits data for asthma and inpatient hospitalizations for myocardial infarction (MI) and heart failure (HF) using case-crossover analysis.
While the regulation is a substantial step forward in the move towards a fully connected driving experience, those following the issue closely know the decision was a long time coming.
The knowledge of RS FC changes may represent a substantial step forward in the MS research field, both for clinical and therapeutic purposes.
Thus, the RAT-TRAP assay constitutes a substantial step forward in the ability to analyse the movement of RNPs in vitro.
The paper by Krakstad et al (2012) in this issue of the BJC takes tissue biomarker studies a substantial step forward in endometrial cancer.
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Prioritizing substantial steps forward in terms of ideology, Zhao's success in 1987 didn't translate immediately into action.
He sees a substantial step forward too in other areas of public life, notably entertainment and athletics.
Dr. Douglas Mann, a heart failure expert at the Houston Veterans Affairs Medical Center and Baylor College of Medicine who also was not involved in the study, called it "a substantial step forward".
We respect that but believe that papers that attempt to corroborate previous findings without taking a substantial step forward, or bringing a new angle to the problem, will have a better home in specialty journals.
"This is a substantial step forward," Mr. Glantz said at a news conference that followed disclosure of the report.
But here is the bottom line: we can embrace this accord, take a substantial step forward, and continue to refine it and build upon its foundation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com