Sentence examples for substantial specificity for from inspiring English sources

Despite this, SH2 domains preserve substantial specificity for peptide ligands, recognizing residues adjacent to the pTyr, particularly those at positions +1 to +5 C-terminal to the critical pTyr [ 19- 21].

The N170 is dominant for faces [ 2] and eyes [ 21], and has shown substantial specificity for faces, typically demonstrating a smaller or absent N170 response for non-face stimuli [ 22].

Finally, because many antibody reagents purported to be specific for "CRP" contains some, or substantial specificity to mCRP, antigen-detection techniques using such reagents may fail to distinguish the specific CRP isoform detected.

While binding to some sites such as stem IIB or IA can show substantial specificity even in their isolated contexts, this does not seem to be the case for the remaining Rev binding sites (Daugherty et al., 2008).

In contrast to other groups of antibiotic peptides, the lantibiotics display a substantial degree of specificity for particular components of bacterial membranes.

There was no substantial difference in specificity for both types of hospital encounters, with values greater than 95% in both settings.

These findings demonstrate that the anti-tumour activity of aspirin has a substantial degree of specificity for CRC cells in vitro, reflecting the epidemiological evidence for a greater protective effect against CRC compared to other cancer types.

Similar to the early development of HCV protease inhibitors, initial attempts to achieve specific inhibitors of HCMV protease relied on peptides and peptidomimetics, taking advantage of the substantial work describing substrate specificity for this enzyme.

Thus, our results show that the similarity in the primary sequences of both kinases is reflected in a chemically similar substrate preference, but the gradual differences that remain, when combined are substantial enough to ensure substrate specificity for the kinases in cellular physiology.

There were no substantial differences in the pooled sensitivity and specificity for cutoff scores from 7 to 10.

In summary, conservation-based gene discovery permits high specificity for function, but often at a substantial cost in sensitivity.