Sentence examples for substantial so that from inspiring English sources

Doses should therefore be substantial so that treatment effects are not missed.

While the normal model may be motivated by asymptotic arguments, in actual applications the number of estimates to be combined is commonly small [ 13, 14] and hence the estimation uncertainty in the between-study variance τ is substantial, so that an adjustment is appropriate and in fact improves operating characteristics [ 7– 15, 15].

The instrument might be particularly useful in situations in which brevity and simplicity of administration are necessary, such as large epidemiological studies, or as in the case of the present parent study, where the scientific focus is not substance use, but where SUD comorbidity is expected to be substantial, so that data on substance use are very important.

They should also be substantial, so that they sit solidly.

Moreover, molecular date estimates can come with substantial uncertainty, so that it can be difficult to draw strong conclusions from molecular date estimates if the associated estimation error is taken into account.

Our aim was also to ensure substantial savings so that all the burden of spending cuts did not fall on further education and training.

But utility functions may be given a variety of substantial interpretations, so that the same formalism may be used to discuss interpersonal comparisons of resources, opportunities, capabilities and the like.

"But more importantly, we need to get to root of the problem and make substantial investments so that at some point in the future we will achieve the Clean Water Act goals of fishable and swimmable water".

The model results are subject to substantial uncertainty so that they must be handled with caution.

Although it is possible to parallelize the core folding algorithms [ 86, 87] this requires substantial overheads so that the gain is small unless massively parallel architectures are used.

Conservative therapies have not been shown to be of substantial benefit, so that the most common treatment for DD remains the surgical excision of the diseased tissue and if necessary correction of finger contractures [ 6, 32- 36].