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Mr Vandermeer does not go as far as his predecessor but accepts that "Heathrow causes substantial sleep disturbance and significant annoyance".Mr Byers has delayed action on the inspector's recommendation that night flights should be more strictly controlled, saying that he is legally obliged to seek advice.
However, considerable data have shown that chronic restriction to this amount of sleep in most humans results in poor performance and the accumulation of substantial sleep debt [ 16].
We mechanically deprived flies of sleep in the second half night (6 hr) in an LD cycle, and confirmed, through the presence of a substantial sleep rebound the following morning, that the flies were successfully deprived.
None of these cases presented significant diurnal fluctuations, worsening of symptoms in the evening or substantial sleep benefit, features often recognized in cases with DOPA-responsive dystonia (Kurian et al., 2011).
9 These associations are of clinical relevance given that pDPN not only results in substantial sleep impairment, 32 but that sleep impairment has been shown to have a direct relationship with metabolic control, including increased risk for and severity of diabetes.
It has been suggested that subjective reports of restfulness following meditation may reflect that meditation is a sleep-like state, or that substantial sleep occurs during bouts of meditation [ 30], but this is not supported by the overwhelming majority of EEG studies (see reference 3 for review), nor did we see any evidence of sleep in our subjects during meditation periods.
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The session was repeated if substantial drowsiness, sleep or movement was detected.
Aging is characterized by substantial changes in sleep architecture altering memory consolidation.
Now there is substantial evidence that sleep deprivation is associated with increased risk for diabetes, obesity and other chronic illnesses.
There may also be substantial changes in sleep length by season.
In primitive surroundings, illumination intensities are substantial during daytime sleep, unlike the dim scotophase in the rodent circadian bifurcation model.
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