Sentence examples for substantial shrinkage from inspiring English sources

People with the condition are born with a brain that is much smaller than usual, often with a substantial shrinkage of the cerebral cortex that seems a throwback to when the human brain was a fraction of present size.

Collagen (Col) hydrogels have poor physicochemical and mechanical properties and are susceptible to substantial shrinkage during cell culture, which limits their potential applications in hard tissue engineering.

Finally, they would study carefully the company's situation and outlook, to make sure that the realizable value of the shares is not likely to suffer a substantial shrinkage.

After 32 courses of the combined chemotherapy, substantial shrinkage of these enlarged lymph nodes were confirmed and she underwent pylorus-preserving pancreaticoduodenectomy.

As states that adopted such insurance reforms without an individual mandate discovered, the upshot might well be the elimination (or substantial shrinkage) of the non-group market as health insurance companies flee for greener pastures.

In clinical practice, many endocrinologists and pituitary surgeons believe that patients presenting with ophthalmoplegia (typically III palsy) without visual field loss may safely be monitored conservatively typically with spontaneous full recovery of the ophthalmoplegia after several weeks and very often with substantial shrinkage of the pituitary mass on the follow-up scan some months later.

A waterfall plot showed substantial tumor shrinkage in most patients in both groups.

Re-simulation during treatment is recommended for selected patients with substantial tumor shrinkage and possible lung expansion.

Although chemotherapy is able to induce substantial tumor shrinkage of variable duration in metastatic and non-resectable TETs, it is not curative in patients with metastatic disease.

On the basis of results of a phase II study showing that patients treated with TPF had a rapid and substantial tumour shrinkage, which may result in an improvement of the local symptoms commonly reported with locally advanced tumours (Schrijvers et al, 2004), it was anticipated that the experimental arm (TPF) would be superior to the control arm (PF) in lowering symptom levels.

Development of anti-cancer therapeutics targeted to specific biological pathways, involved in tumour growth and progression, and inducing cytostasis rather than substantial tumour shrinkage, has led to a need for non-invasive biomarkers reporting on drug action and tumour response beyond simple radiological assessment based on lesion size.