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Fillingm et al. (2000) reviewed literature in sex, gender and pain and found substantial sex differences in clinical and experimental procedure [34].
While men are at higher risk than women to default ART [17], one study reported no substantial sex differences in the benefits of ART [18].
The prevalence of overweight/obesity and several CVRFs was high, with substantial sex differences.
No substantial sex differences were found in the prevalence of eczema at 2 years.
Furthermore, genes showing similar basal expression between sexes may exhibit substantial sex differences in response to stressors.
The analysis of length of time in a specific income position showed substantial sex differences in poor health.
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This was likely due to the substantial sex difference in central obesity (1.6% [95% CI 1.2 2.0] in men versus 29.7%[955% CI 28.4 31.0] in women), which is required in the IDF definition of MetS.
Small but significant sex differences were observed.
Prospective studies in Germany and Sweden and surveillance data from Germany show no differences in clinical cases (except only a slight preponderance among women) that would point to substantial sex-specific differences in the development of clinical disease (5 – 7 ).
We do not expect substantial sex-specific differences in gene expression at E11.5 because most male-specific development begins with testosterone synthesis in the gonads.
Additionally we demonstrated substantial sex-specific differences in IgE when considering multi-gene models, and in canonical pathway analyses of IgE level.
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