Sentence examples for substantial selectivity from inspiring English sources

However, the β5c-selective inhibitor compound 14, which was the most isoform-selective compound in vitro, displayed substantial selectivity for the constitutive proteasome in cells.

The novel pyrazole Pyr10 displayed substantial selectivity for TRPC3-mediated responses (18-fold) and the selective block of TRPC3 channels by Pyr10 barely affected mast cell activation.

However, although the binding strength was lower, both media exhibited substantial selectivity at pH 7.5.

This also explains the substantial selectivity occurring despite the fact that the noble metal ions all have a rather similar globular geometry.

Moreover, the crystal structure of HKUST-1 has a substantial selectivity factor of 7 1 towards CO2 over N2 in room temperature at around 35 kPa [39].

The hydrosilylation of allyl compounds is very important for the industrial production of γ-substituted propylsilanes; however, it is also a process known to suffer from either substantial selectivity issues or short catalyst lifetimes.

Qualities such as sharp cutoff, high selectivity, substantial size reduction, and low insertion loss, have all been achieved.

In this study substantial changes in selectivity would have been difficult to interpret, since they could have arisen from either monitoring of new neurons, or the shifting selectivity of the same neuron.

However, there is evidence from TbNMT inhibitors that a substantial window of selectivity can be derived between HsNMT1 and TbNMT despite highly similar active site structures.

The substantial improvement in selectivity for ML241 and the remarkably clean profile for ML240 bode well for their utility as in vivo probes and the therapeutic potential of this chemotype in general.

A low recycle ratio can significantly reduce the required membrane selectivity without substantial energy penalty.